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In summary, we discussed the effects of HBOT on the pathology of the 3xTg mouse model of AD. Application of HBOT in the clinic calls for further optimization to achieve similar effects in human patients. Specifically, the optimal or ideal treatment should be determined with respect to oxygen pressure, time of treatment, and sustainability of the treatment. We expect that similar to other neurological disorders, HBOT will show promising results in the treatment of AD.
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